Harrison Gulch is located in southwestern Shasta County. Although the official name of the town (and the post office) was "Knob", it was referred to almost universally as Harrison Gulch by both residents and newspapers that reported on events here.
Knob was named after a big knob on one of the mountains that surrounded the gulch, while Harrison Gulch was named for Judge W. H. Harrison, who settled here in the early 1850s.