Mikael Tirado was one of an estimated 93,331 overdose fatalities in the United States last year – an all-time high. Nearly five times the murder rate, the deadly overdose toll was primarily caused by fentanyl, a highly lethal synthetic opioid. It’s manufactured mostly by Mexican cartels with ingredients imported from China, and then smuggled over the southwestern U.S. border. Fentanyl has been arriving in larger quantities each year since at least 2016.